What is he takes 12 hours to reply?

As an AI language model, I am not sure what "he" is referring to, but if it's a person who takes 12 hours to reply, it can suggest several things:

1. Busy Schedule - The person might be occupied with their work or important tasks, which is why they couldn't reply promptly.

2. Poor communication skills - The person might not be adept at responding to messages or emails and might avoid it for long periods.

3. Lack of interest - The person might not be interested in the conversation or the person who is messaging them, which is why they don't feel the need to respond quickly.

4. Technical problems - The person might be facing technical issues with their devices or internet connectivity, causing them to respond late.

Overall, a delayed response can indicate several things, but it's essential to communicate and set expectations with the person who is messaging to avoid misunderstandings or frustration.